All the 19 sequenced Salmonella Kentucky isolates were identified as ST198. We also investigated population evolutionary dynamics through phylogenetic and pangenome analyses with additional publicly available Salmonella Kentucky ST198 genomes (n=229). This study aimed to investigate the antimicrobial resistance profile and the genotypic relatedness of Salmonella Kentucky isolated from animal sources in Ethiopia and Kenya (n=19). enterica serovar Kentucky has become a significant public health problem, especially in East Africa.

Since its emergence in the beginning of the 90’s, multidrug-resistant (MDR) Salmonella enterica subsp.

9Global One Health Initiative (GOHi), The Ohio State University, Columbus, OH, United States.

8Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.

7Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.

6Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.

5Department of Preventive Veterinary Medicine, Veterinary School, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.

4Department of Technology, Sao Paulo State University (FCAV-Unesp), Jaboticabal, Brazil.

3Department of Animal Science, Center for Agricultural Sciences, Federal University of Paraiba (CCA/UFPB), Areia, Brazil.

2Department of Preventive Veterinary Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH, United States.

1Department of Pathology, Theriogenology, and One Health, Sao Paulo State University (FCAV-Unesp), Jaboticabal, Brazil.

Mauro de Mesquita Sousa Saraiva 1,2, Valdinete Pereira Benevides 1, Núbia Michelle Vieira da Silva 3, Alessandro de Mello Varani 4, Oliveiro Caetano de Freitas Neto 5, Ângelo Berchieri Jr 1, Enrique Jesús Delgado-Suárez 6, Alan Douglas de Lima Rocha 3, Tadesse Eguale 7, Janet Agnes Munyalo 8, Samuel Kariuki 8, Wondwossen Abebe Gebreyes 2,9 and Celso José Bruno de Oliveira 3,9*

Douglas mesquita silva